Trevicta 350 Mg Injection

Trevicta 350 injections contain anti-psychotic Paliperidone, which works by strongly binding to serotonin and dopamine D2 receptors, blocking alpha-1 adrenergic receptors, and, to a lesser extent, H1 and alpha-2 adrenergic receptors, which helps in relieving psychotic symptoms.

Trevicta 350 uses

Trevicta 350 mg injections are used to treat schizophrenia, a disease characterized by delusions and hallucinations, as the patient sees, hears, or feels things that do not exist in reality.

Trevicta 350 dosage

• The appropriate dose is determined by the doctor.

• The usual dose is one injection every 3 months, but under the conditions that the patient receives Paliperidone monthly, and has received at least 6 times the same dose, in addition to a clinically stable patient's condition.

• Trevicta injections are used by intramuscular injections.

• The syringe should be firmly shaken for 15 seconds, and the Trevicta injection should be given within 5 minutes after shaking.

Trevicta injection side effects 

• Insomnia.

• Increase blood sugar levels.

• Weight gain.

• Depression.

• Hyperprolactinemia.

• respiratory infection.

• dizziness.

• headache.

• High blood pressure.

• Increased heart rate.

• Nausea and vomiting.

• Joint pain.

• Amenorrhea.

Trevicta Contraindications

Trevicta is not used for allergies to the drug's ingredients.

Trevicta use precautions

• Care should be taken before using Trevicta, especially:

• Patients with acute agitation or severe psychotic conditions.

• Arrhythmias.

• Trevicta may cause Neuroleptic malignant syndrome, which may cause high temperature and muscle rigidity, and you should stop using the drug if suffering from that syndrome.

• The drug may cause tardive dyskinesia, such as rhythmic involuntary movements in the face or tongue, in which case it should be discontinued.

• The use of the drug may lead to a decrease in the number of white blood cells.

• Blood sugar levels should be monitored in patients receiving the drug, especially as it may aggravate diabetes.

• The drug is used with caution in case of suffering from a tumor that is prolactin-dependent.

• Trivecta is used with caution in case of heart problems or blood pressure.

• Care should be taken before using Trevicta with a history of epilepsy.

• The dose of the drug should be adjusted in case of renal insufficiency, and Trevicta is not used in case of moderate or severe renal insufficiency.

• The doctor should be consulted in case of priapism and continued erection for more than 4 hours after obtaining the medication.

Trevicta and pregnancy

Trevicta 350 may harm the fetus or newborn child, especially as it is a long-acting medication, so it is only used during pregnancy if necessary and under the supervision of a doctor.

Trevicta and lactation

Trevicta may travel through breast milk to the infant, so the drug is not recommended during breastfeeding.

Drug interactions

The doctor should be consulted before getting Trevicta injections, especially with other medications, such as:

• Antiarrhythmic drugs.

• Antihistamines (allergic drugs).

• Antibiotics.

• Parkinson's drugs.

• Other antipsychotics.